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Cardiometabolic outcome trials Older women taking orlistat had improved biventricular diastolic function and beneficial restructuring of their myocardium, producing a lower left ventricular mass, at the end of 6 months, although the cardiac outcomes were likely the result of weight loss rather than independent effect of orlistat [105]

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Finally the weight lost by the group of 1mg dose was slightly more than that achieved by the world’s largest selling prescription obesity medication in similar trials over the same period, without its troublesome side effects