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While retaining their binding to cartilage, these fragments were able to carry payloads such as an MMP-cleavable form of viral IL-10 60 and soluble TNF receptor II, 33 enabling the in vivo imaging of murine OA cartilage
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To confirm the prediction, we found the binding region of miR-146a-3p and AQP4 (Figure 5F) and transfected miR-146a-3p into astrocytes
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