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found a very high incidence of elevation of transaminase values with PTU in comparison with methimazole.19 Methimazole-induced hepatotoxicity usually develops in the first few weeks of drug consumption with an estimated incidence of 0.1-0.2%.6,20 The figure of hepatic injury induced by antithyroid agents seems different according the histopathological findings

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Although neither biomarker is currently included in clinical guidelines for cardiovascular screening, their strong prognostic associations in inflammatory populations highlight potential utility for identifying individuals at elevated cardiovascular risk, an approach that could also be useful for CVID