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PMCs migrate and proliferate on the serosal lining (Tsai et al., 2018) and differentiate into myo-fibroblasts (EMT), which may promote fibrotic conversion (Sandoval et al., 2016) Changes in the gene expression and phenotype of PMCs, making them deposit more collagens and fibronectin and increasing their motility, which facilitate the development of peritoneal fibrosis (Strippoli et al., 2016)
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