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However, excess ROS production can lead to oxidative stress (OS) (Grimm and Eckert, 2017), which causes damage to lipids, proteins and deoxyribonucleic acid (DNA), leading eventually to inflammation, apoptotic cell death, and tissue damage (Fig
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Airspace enlargement is a hallmark of lung emphysema and was observed in mice treated with BSO and exposed to CS for as little as 15 days, whereas these types of changes normally take up to 6 months in this model
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