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67 In sepsis-induced acute liver injury, luteolin modulated liver macrophage polarization from the pro-inflammatory M1 phenotype to the anti-inflammatory M2 phenotype, thereby exerting protective effects via the TLR4/MyD88/NF-κB signaling pathway, as demonstrated in a sepsis-induced acute hepatic injury mouse model, mouse bone marrow-derived macrophages, and RAW264.7 cells
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