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In cultured human somatic cells (fetal fibroblast lines), addition of Epithalon has been reported to induce expression of the catalytic subunit of telomerase (TERT), to give measurable telomerase activity by TRAP assay in cells that lack it, and to lengthen telomeres over subsequent passages, with the cultures continuing to divide past the point at which control cultures reached replicative senescence

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This article reports the case of a dog whose initial condition and its treatment led to sequelae that affected his overall prognosis